Vertical with disposable bags and mixers
The HyClone S.U.B. is based on a conventional stirred tank
approach rather than less characterized designs. The HyClone S.U.B.
r is a fully functional bioreactor vessel including single-use
contact surfaces for mixing, venting, sparging and temperature
sensing. Ports are provided for monitoring, sampling and liquid
transfers. The unique mixing system (patent pending) provides
overhead mixing while maintaining sterility and integrity. A
re-usable outer support container also provides a mixer motor,
heating/cooling, control unit for integration with an external
control system and a mobile skid.
Applikon is an
authorized integrator for the HyClone S.U.B. bioreactors.
ez-Control
ez-Control is the most economical and advanced choice for your
process control in your HyClone S.U.B. Systems. Plug-and-play
"ez-Control for S.U.B." system based on the standard HyClone S.U.B.
interface. Most control suppliers have experience with HyClone
S.U.B. integration but where we make a difference is in the economy
of our control solution in combination with its flexibility, ease
of operation and advanced control capabilities. In combination with
services available through our Technical Support team we offer the
best solution for HyClone S.U.B. automation currently available in
the market. You can source the control system and HyClone S.U.B.
direct from Applikon and let us supply an integrated solution.This
turn-key supply of the integrated S.U.B. and control system offers
peace of mind.
Bioprocessing Expertise
Since we manufacture both single-use and re-usable bioreactor
systems from microliter scale up to full production scale, this
gives us unique capabilities to support our customers and guide
them from basic research to production in the shortest possible
time. We have extensive experience operating bioreactor systems on
all scales in our laboratories enabling us to offer real set-up and
applications support to our customers.
Advantages of the HyClone S.U.B.
- Scalability - The HyClone S.U.B. offers a technology for both
larger and smaller volume systems for research and process
development to meet the needs of clients.
- Alternative Sparging Systems - Although the porous membrane in
the current standard HyClone S.U.B. BPC performs well for a wide
range of applications, the product is also supplied with an open
pipe and (optional) micro porous "frit".
- Single-use Non-invasive Sensors - Alternative systems are
becoming accepted by bioprocessing customers, and modified port
structures be integrated into the HyClone S.U.B. The ez-Control is
capable of measuring both classical sensors for pH and Dissolved
Oxygen as well as FLuorophor type sensors.
The combination of ez-Control and HyClone S.U.B. offers
the advantages of Single-Use Processing:
- No cleaning or sterilization (apart from the monitoring
probes)
- Reduced turnaround and setup times
- Minimal validation
- Reduced investment and running costs
- Increased flexibility of manufacturing capacity
- Reduced time-to-market for your product
The HyClone S.U.B. product range provides working
volumes from 25-1000 L, allowing seamless scale up.